Evolutionary Analysis 5th Edition Herron Freeman – Test Bank
Evolutionary Analysis, 5e (Herron/Freeman)Chapter 1 A Case for Evolutionary Thinking: Understanding HIV1) In which of the following regions has AIDS killed the largest number of individuals? A) IndiaB) Sub-Saharan AfricaC) United StatesD) ChinaE) United KingdomAnswer: BSection: 1.1Skill: Knowledge/Comprehension2) The HIV virus contains all of the following components except ________. A) integraseB) double-stranded RNAC) single-stranded RNAD) reverse transcriptase E) proteaseAnswer: BSection: 1.1Skill: Knowledge/Comprehension3) The acronym HIV stands for which of the following? A) human intercellular virusB) human immune virusC) human immunodeficiency virusD) human immunity virusE) human immunodeficiency vector Answer: CSection: 1.1Skill: Knowledge/Comprehension4) Which of the following enzymes is responsible for transcribing viral RNA into DNA? A) RNA polymeraseB) reverse transcriptaseC) DNA polymeraseD) reverse integrase E) RNA duplicase Answer: B Section: 1.1Skill: Knowledge/Comprehension1Copyright © 2014 Pearson Education, Inc.
5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what type of cells are these proteins typically observed?A) plasma cellsB) dendritic cellsC) effector helper T cells D) memory helper T cells E) both C and DAnswer: ESection: 1.1Skill: Knowledge/Comprehension6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood drops below what concentration?A) 2,000 cells per cubic millimeterB) 1,000 cells per cubic millimeterC) 500 cells per cubic millimeter D) 200 cells per cubic millimeter E) No CD4 T cells are observed. Answer: DSection: 1.1Skill: Knowledge/Comprehension7) Which of the following drug categories are used to treat HIV infections? A) integrase inhibitorsB) protease inhibitorsC) reverse transcriptase inhibitorsD) DNAse inhibitors E) fusion inhibitors Answer: DSection: 1.2Skill: Knowledge/Comprehension8) Coreceptor inhibitors block HIV infection by preventing which of the following? A) binding of the HIV virion onto the plasma membraneB) binding of the HIV virion onto the CCR5 receptorC) binding of the HIV virion onto the gp120 proteinD) degrading the coreceptor so the virion cannot attach E) binding of the HIV virion onto the CD4 receptor Answer: BSection: 1.2
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9) What is the effect of the ∆32 allele of CCR5 on HIV binding?A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell B) does not appear on the surface of CD4 T cellsC) appears on the surface of the CD4 T cells and inactivates the virion upon bindingD) interferes with binding of the virion to the CD4 receptor proteinE) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding Answer: BSection: 1.3Skill: Application/Analysis10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following populations?A) AfricansB) JapaneseC) North Americans D) EuropeansE) South Americans Answer: DSection: 1.3Skill: Knowledge/Comprehension